Recombinant Mouse IL-2 Receptor Subunit Beta/IL-2RB/CD122 (C-6His)
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- 表达系统： HEK293 Cells
- 蛋白编码： P16297
| 别称 |
CD122;High affinity IL-2 receptor subunit beta;IL15Rbeta;IL-15Rbeta;IL-2 receptor subunit beta;Il-2/15Rbeta;IL-2R subunit beta;IL-2RB;Il-2Rbeta;Interleukin-2 receptor subunit beta;p70;p70-75;Il2rb;IL-2RβIL15RB;Interleukin-15 receptor subunit beta;p75
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| 表达系统 |
HEK293 Cells
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| 序列 |
Ala27-Glu240
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| 蛋白编码 |
P16297
|
| 种属 |
Mouse
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| 计算分子量 |
26.1 kDa
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| 表观分子量 |
40-60 kDa
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| 标签 |
C-His
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 90 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.
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实验操作视频
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