Recombinant Mouse IL-5 Protein(Fc Tag)

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- 表达系统: Mammalian
- 蛋白编码: P04401
表达系统 |
Mammalian
|
序列 |
Met1-Gly133
|
蛋白编码 |
P04401
|
种属 |
Mouse
|
计算分子量 |
39.5 kDa
|
表观分子量 |
40-60 kDa
|
标签 |
C-Fc
|
生物活性 |
Not validated for activity
|
纯度 |
> 90% as determined by reducing SDS-PAGE.
|
内毒素 |
< 1.0 EU/mg of the protein as determined by the LAL method
|
保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
|
复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
|
背景 |
IL-5 (Interleukin-5) is a secreted cytokine that is expressed as a covalent dimer. It is produced by activated Th2 cells, eosinophils, mast cells, and iNKT cells and promotes eosinophilic and basophilic differentiation and activation. IL-5 signals through a receptor complex containing IL-5 R alpha and the Common beta Chain/CD131 on eosinophils and basophils. Naturally occurring soluble forms of IL-5 R alpha retain the ability to bind IL-5 and limit its bioavailability.
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实验操作视频
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