Recombinant Mouse Leptin
Price:
- 表达系统： E.coli
- 蛋白编码： Q544U0
| 别称 |
LEP;Leptin;OB;OBS;Obese Protein;Obesity Factor
|
| 表达系统 |
E.coli
|
| 序列 |
Val22-Cys167
|
| 蛋白编码 |
Q544U0
|
| 种属 |
Mouse
|
| 计算分子量 |
16.1 kDa
|
| 表观分子量 |
14 kDa
|
| 标签 |
None
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 300mM NaCl, pH7.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
|
| 背景 |
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have revealed the influence of Leptin in reducing body weight and regulating blood glucose level. When mutations are introduced in obese gene, mice with impaired function of leptin are massively obese and in high risk of diabetes. Leptin deficiency reduces metablic rate. Leptin deficient mice are less active and with lower body temperature than normal animals. Human Leptin shares approximately 84% sequence identity with the mouse protein. Human Leptin consists of 167 amino acid residue including a 21 amino acid residue signal sequence and 146 amino acid residue mature protein sequence.
|
-
Neuroprotective Effects of Leptin on the APP/PS1 Alzheimer’s Disease Mouse Model: Role of Microglial and Neuroinflammation
IF: 4.000Journal： Degenerative Neurological and Neuromuscular Disease (2023)PMID：37905186
实验操作视频
新品推荐
Recombinant Mouse CXCL1 Protein(GST Tag)
Recombinant Human BCL2 Protein(GST Tag)
Recombinant Mouse Agrp Protein(GST Tag)
Recombinant Human S100A9 Protein(Trx Tag)
Recombinant Mouse Ceacam1 Protein(His Tag)
Recombinant Mouse Fetuin-A Protein(His Tag)
Recombinant Mouse CD3E Protein(Trx Tag)
Recombinant Human CD44 Protein(Trx Tag)
联系我们
