Recombinant Rat IL-4 Protein
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- 表达系统： HEK293 Cells
- 蛋白编码： P20096
| 别称 |
Interleukin;B-cell growth factor;B-cell stimulatory factor;Lymphocyte stimulatory factor;BCGF1;B-cell IGG differentiation factor;B-cell stimulatory factor 1;BCGF-1;Binetrakin;BSF1;Interleukin-4;Lymphocyte stimulatory factor 1;Pitrakinra;Il4;BSF-1;Lymphocy;Il 4;B-cell growth factor 1;Il-4;IL4、BCGF-1、BCGF1、BSF-1、BSF1
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| 表达系统 |
HEK293 Cells
|
| 序列 |
Met1-Ser147
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| 蛋白编码 |
P20096
|
| 种属 |
Rat
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| 计算分子量 |
16.5 kDa
|
| 表观分子量 |
17 kDa
|
| 标签 |
C-His
|
| 生物活性 |
Not validated for activity
|
| 纯度 |
> 90% as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU/mg of the protein as determined by the LAL method
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
Participates in at least several B-cell activation processes as well as of other cell types.
It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.
Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
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Osteosarcoma-targeting PtIV prodrug amphiphile for enhanced chemo-immunotherapy via Ca2+ trapping
IF: 9.400Journal： Acta Biomaterialia (2024)
实验操作视频
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