Recombinant Rhesus Macaque Angiotensin-Converting Enzyme 2/ACE-2 (C-10His)-Elabscience伊莱瑞特【官网】

Recombinant Rhesus Macaque Angiotensin-Converting Enzyme 2/ACE-2 (C-10His)

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货号：PKSQ050119
说明书

说明书

Recombinant Rhesus Macaque Angiotensin-Converting Enzyme 2/ACE-2 (C-10His)

Price: ¥5250.00 ¥1666.00

Size:

50 μg 10 μg

表达系统： HEK293 Cells
蛋白编码： ACI04564.1
应用性： ELISA

别称	ACE-Related Carboxypeptidase;ACE2;ACEH;Angiotensin-Converting Enzyme 2;Angiotensin-Converting Enzyme Homolog;Metalloprotease MPROT15
表达系统	HEK293 Cells
序列	Gln18-Val739
蛋白编码	ACI04564.1
种属	Rhesus Macaque
计算分子量	85.1 kDa
表观分子量	90-120 kDa
标签	C-His
生物活性	Immobilized Rhesus Macaque ACE-2-His(Cat#PKSQ050119)at 5μg/ml (100 μl/well) can bind 2019-nCoV S Protein RBD-SD1-mFc(Cat#PKSR030476). The ED50 of Recombinant 2019-nCoV S Protein RBD-SD1-mFc(Cat#PKSR030476) is 16.8 ng/ml.
纯度	> 95 % as determined by reducing SDS-PAGE.
内毒素	< 1.0 EU per μg of the protein as determined by the LAL method.
保存条件	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
运输条件	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
制剂	Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 150mM NaCl, 1mM ZnCl₂, pH 7.5.
复溶方法	Not Applicable
背景	Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.

> 95 % as determined by reducing SDS-PAGE.

Immobilized Rhesus Macaque ACE-2-His(Cat#PKSQ050119)at 5μg/ml (100 μl/well) can bind 2019-nCoV S Protein RBD-SD1-mFc(Cat#PKSR030476). The ED50 of Recombinant 2019-nCoV S Protein RBD-SD1-mFc(Cat#PKSR030476) is 16.8 ng/ml.