Recombinant Rhesus macaque CD47/IAP Protein (Fc Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： F7A802
| 别称 |
Antigenic Surface Determinant Protein OA3;CD47;IAP;Integrin-Associated Protein;Leukocyte Surface Antigen CD47;MER6;Protein MER6
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| 表达系统 |
HEK293 Cells
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| 序列 |
Gln19-Pro139
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| 蛋白编码 |
F7A802
|
| 种属 |
Rhesus macaque
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| 计算分子量 |
40.8 kDa
|
| 表观分子量 |
60-90 kDa
|
| 标签 |
C-Fc
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| 生物活性 |
Not validated for activity
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 100 mM Glycine, pH 7.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
CD47(Integrin-Associated Protein,IAP) is a 40-60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
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实验操作视频
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