AF/LE Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]
![AF/LE Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： FCM
- 亚型： Rat IgG2b, κ
- 宿主： Rat
| Alternate Names | B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, B7 homolog 1, B7-H, B7-H1, Programmed cell death ligand 1 |
| Clone No | |
| Isotype | Rat IgG2b, κ |
| Leadtime |
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| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
|
| Background |
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
|
| Immunogen | Recombinant Mouse CD274 protein |
| Abbre | CD274/PD-L1 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Applications | |
| Research Areas | Cancer Biomarkers;Costimulatory Molecules;Immunology |
| Concentration | ≥ 1 mg/mL |
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12个月 |
| Shipping |
Ice bag |
C57/BL6 Mouse splenocytes were stained with 0.2 μg AF/LE Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] (Right) and 0.2 μg Rat IgG2b, κ Isotype Control (Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.
| E-AB-F1132A | Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] | 100 μg , 25 μg |
| E-AB-F1132B | Biotin Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] | 100μg , 25μg |
| E-AB-F1132C | FITC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] | 100Tests , 50Tests , 100Tests×2 |
| E-AB-F1132D | PE Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] | 100Tests , 50Tests , 100Tests×2 |
| E-AB-F1132E | APC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] | 100Tests , 50Tests , 100Tests×2 |
| E-AB-F1132L | Elab Fluor® 488 Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] | 100Tests , 50Tests , 100Tests×2 |
| E-AB-F1132M | Elab Fluor® 647 Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] | 100Tests , 50Tests , 100Tests×2 |
| E-AB-F1132UC | FITC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] | 100μg , 25μg |
| E-AB-F1132UD | PE Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] | 100μg , 25μg |
| E-AB-F1132UE | APC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] | 100μg , 25μg |
| E-AB-F1132UL | Elab Fluor® 488 Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] | 100μg , 25μg |
| E-AB-F1132UM | Elab Fluor® 647 Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] | 100μg , 25μg |
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