Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]-Elabscience伊莱瑞特【官网】

Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]

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货号：E-AB-F1132A
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说明书

说明书

Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]

Price: ¥400.00 ¥180.00

Size:

100 μg 25 μg

应用性： FCM
亚型： Rat IgG2b, κ
宿主： Rat

Alternate Names	B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, B7 homolog 1, B7-H, B7-H1, Programmed cell death ligand 1
Clone No	10F.9G2
Isotype	Rat IgG2b, κ
Leadtime	咨询
Verified Samples	Verified Samples in FCM: C57/BL6 Mouse splenocytes
Dilution	FCM 2 μg/mL(1×10⁵-5×10⁵ cells)
Background	CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
Immunogen	Recombinant Mouse CD274 protein
Abbre	CD274/PD-L1
Swissprot	Q9EP73
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Purification Method	>98%, Protein A/G purified
Applications	FCM
Research Areas	Cancer Biomarkers;Costimulatory Molecules;Immunology
Concentration	≥ 1 mg/mL
Conjugation	Unconjugated
Storage Buffer	PBS, pH 7.2. Contains 0.05% proclin 300.
Storage	Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Expiration Date	12个月
Shipping	Ice bag

C57/BL6 Mouse splenocytes were stained with 0.2 μg Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2](Right) and 0.2 μg Rat IgG2b, κ Isotype Control(Left), followed by Alexa Fluor^® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.

Characterization of immunomodulating agents from Staphylococcus aureus for priming immunotherapy in triple-negative breast cancers

IF: 3.800

Journal： Scientific Reports (2024)

DOI：10.1038/s41598-024-51361-8

Reactivity：Mouse

Sample Type：4T1 cell-xenograft

E-AB-F11320	AF/LE Purified Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]	100 μg , 25 μg
E-AB-F1132B	Biotin Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]	100μg , 25μg
E-AB-F1132C	FITC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]	100Tests , 50Tests , 100Tests×2
E-AB-F1132D	PE Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]	100Tests , 50Tests , 100Tests×2
E-AB-F1132E	APC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]	100Tests , 50Tests , 100Tests×2
E-AB-F1132L	Elab Fluor® 488 Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]	100Tests , 50Tests , 100Tests×2
E-AB-F1132M	Elab Fluor® 647 Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]	100Tests , 50Tests , 100Tests×2
E-AB-F1132UC	FITC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]	100μg , 25μg
E-AB-F1132UD	PE Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]	100μg , 25μg
E-AB-F1132UE	APC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]	100μg , 25μg
E-AB-F1132UL	Elab Fluor® 488 Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]	100μg , 25μg
E-AB-F1132UM	Elab Fluor® 647 Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]	100μg , 25μg