APC Anti-Human CD273/PD-L2 Antibody[24F.10C12]
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- 应用性： FCM
- 亚型： Mouse IgG2a, κ
- 宿主： Mouse
| Alternate Names | CD273PDCD1L2PDL2, B7DC |
| Cellular Localization |
Membrane
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| Clone No | |
| Isotype | Mouse IgG2a, κ |
| Leadtime |
咨询
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| Background |
CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.
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| Abbre | CD273 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype Control | |
| Applications | |
| Form | Liquid |
| Concentration | 5 μL/Test |
| Conjugation | APC |
| Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
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Identifying a locus in super-enhancer and its resident NFE2L1/MAFG as transcriptional factors that drive PD-L1 expression and immune evasion
IF: 6.200 -
The 3′ Non-Coding Sequence Negatively Regulates PD-L1 Expression, and Its Regulators Are Systematically Identified in Pan-Cancer
IF: 3.500 -
A Tumor-Specific Super-Enhancer Drives Immune Evasion by Guiding Synchronous Expression of PD-L1 and PD-L2
IF: 7.815
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
