APC Anti-Human CD45 Antibody[HI30]
![APC Anti-Human CD45 Antibody[HI30]](http://files.elabscience.cn/assets/images/loading.png)
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- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Alternate Names | CD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200 |
Cellular Localization |
Membrane
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Clone No | |
Isotype | Mouse IgG1, κ |
Leadtime |
咨询
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Background |
CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
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Abbre | CD45 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Isotype Control | |
Applications | |
Form | Liquid |
Concentration | 5 μL/Test |
Conjugation | APC |
Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
Spectrum | ![]() |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12个月 |
Shipping |
冰袋 |
Gene ID |
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EMF treatment delays mesenchymal stem cells senescence during long-term in vitro expansion by modulating autophagy
IF: 4.600Journal: Frontiers in Cell and Developmental Biology (2024)Reactivity:Rat -
Human mesenchymal stem cells derived exosomes improve ovarian function in chemotherapy-induced premature ovarian insufficiency mice by inhibiting ferroptosis through Nrf2/GPX4 pathway
IF: 3.800
E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |