APC Anti-Human IL-21 Antibody[3A3-N2]
![APC Anti-Human IL-21 Antibody[3A3-N2]](http://files.elabscience.cn/assets/images/loading.png)
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- 应用性: ICFCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Alternate Names | IL-21, Interleukin-21, Za11 |
Cellular Localization |
Secreted
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Clone No | |
Isotype | Mouse IgG1, κ |
Leadtime |
咨询
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Background |
Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
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Abbre | IL-21 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Isotype Control | |
Applications | |
Form | Liquid |
Concentration | 5 μL/Test |
Conjugation | APC |
Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
Spectrum | ![]() |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12个月 |
Shipping |
冰袋 |
Gene ID |
E-CK-A091 | Cell Stimulation and Protein Transport Inhibitor Kit | 500Assays , 200Assays , 100Assays , 50Assays |
E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
E-CK-A109 | Intracellular Fixation/Permeabilization Buffer Kit | 500Assays , 100Assays , 50Assays |