APC Anti-Mouse CD150/SLAM Antibody[TC15-12F12.2]
![APC Anti-Mouse CD150/SLAM Antibody[TC15-12F12.2]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100μg
25μg
- 应用性： FCM
- 亚型： Rat IgG2a, λ
- 宿主： Rat
| Alternate Names | CD 150, Signaling lymphocytic activation molecule, Slam, Slamf1 |
| Cellular Localization |
Membrane
|
| Clone No | |
| Isotype | Rat IgG2a, λ |
| Leadtime |
咨询
|
| Background |
CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.
|
| Abbre | CD150 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype Control | |
| Applications | |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Conjugation | APC |
| Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD150 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
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