APC Anti-Mouse CD206/MMR Antibody[C068C2]
![APC Anti-Mouse CD206/MMR Antibody[C068C2]](http://files.elabscience.cn/assets/images/loading.png)
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- 应用性： FCM;ICFCM
- 亚型： Rat IgG2a, κ
- 宿主： Rat
| Alternate Names | MMR, MR, MRC1, macrophage mannose receptor, mannose receptor |
| Cellular Localization |
Membrane;Endosome
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| Clone No | |
| Isotype | Rat IgG2a, κ |
| Leadtime |
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| Background |
CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.
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| Abbre | CD206 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype Control | |
| Applications | |
| Form | Liquid |
| Concentration | 5 μL/Test |
| Conjugation | APC |
| Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
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O-linked β-N-acetylglucosamine transferase regulates macrophage polarization in diabetic periodontitis: In vivo and in vitro study
IF: 4.2 -
Diffuse large B-cell lymphoma cell-derived exosomal NSUN2 stabilizes PDL1 to promote tumor immune escape and M2 macrophage polarization in a YBX1-dependent manner
IF: 3.8Journal： ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2025)Reactivity：Human -
Cationic liposomes encapsulating IL-2 selectively induce apoptosis and significantly reduce the secretion of cytokines on M1-murine polarized macrophages
IF: 3.7 -
Methotrexate loaded extracellular vesicles attenuate periodontitis by suppressing ACSL1 and promoting anti-inflammatory macrophage
IF: 3.2 -
NLRP3 regulates macrophage function by M-CSF/M-CSFR signaling in acute radiation-induced lung injury
IF: 3.2 -
Biomimetic Peptide Nanonets: Exploiting Bacterial Entrapment and Macrophage Rerousing for Combatting Infections
IF: 15.8Journal： ACS Nano (2024)Reactivity：MouseSample Type：spleen tissue,peritoneal lavage fluid -
Metabolism/Immunity Dual-Regulation Thermogels Potentiating Immunotherapy of Glioblastoma Through Lactate-Excretion Inhibition and PD-1/PD-L1 Blockade
IF: 14.3Journal： Advanced Science (2024)Reactivity：MouseSample Type：GL261 cell-Xenograft -
Pregnane X Receptor Activation in Liver Macrophages Protects against Endotoxin-Induced Liver Injury
IF: 14.3 -
Dual-Drug Nanomedicine Assembly with Synergistic Anti-Aneurysmal Effects via Inflammation Suppression and Extracellular Matrix Stabilization
IF: 13.0 -
Legumain-Guided Ferulate-Peptide Self-Assembly Enhances Macrophage-Endotheliocyte Partnership to Promote Therapeutic Angiogenesis After Myocardial Infarction
IF: 10.0
| E-CK-A105 | 10×ACK Lysis Buffer | 500 mL , 200 mL , 100 mL |
| E-CK-A107 | Cell Staining Buffer | 500 mL , 200 mL , 100 mL |
| E-CK-A109 | Intracellular Fixation/Permeabilization Buffer Kit | 500 Assays , 100 Assays , 50 Assays |
