Axl Polyclonal Antibody(Capture/Detector)

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- 宿主: Rabbit
- 反应性: Human
- 应用性: ELISA Capture/Detector;WB
Verified Samples |
Verified Samples in ELISA: Recombinant Human Axl protein, Human serum, Human plasma Verified Samples in WB: HeLa |
Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL, WB 1:500-1:1000 |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Immunogen | Recombinant Human Axl protein expressed by Mammalian |
Abbre | Axl |
Synonyms | AXL |
Swissprot | |
Calculated MW | 98 kDa |
Observed MW | 138 kDa |
Concentration | 1 mg/mL |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Purification Method | Antigen Affinity Purification |
Research Areas | Cell Biology, Signal Transduction, Cancer, Neuroscience |
Conjugation | Unconjugated |
Background | The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.AXL (AXL Receptor Tyrosine Kinase) is a Protein Coding gene. Diseases associated with AXL include Lymphocytic Choriomeningitis and Femoral Neuropathy. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MERTK. |
PDMH100293 | Recombinant Human AXL/UFO Protein(Fc Tag) | 100 μg , 20 μg |