Biotin Anti-Human CD127/IL-7RA Antibody[A019D5]
![Biotin Anti-Human CD127/IL-7RA Antibody[A019D5]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100μg
25μg
- 应用性： FCM
- 亚型： Mouse IgG1, κ
- 宿主： Mouse
| Alternate Names | CD127, CDw127, IL-7RA, IL-7Rα, Interleukin-7 receptor subunit alpha |
| Cellular Localization |
Membrane
|
| Clone No | |
| Isotype | Mouse IgG1, κ |
| Leadtime |
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| Background |
CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.
|
| Abbre | CD127 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype Control | |
| Applications | |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Conjugation | Biotin |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
Human peripheral blood lymphocytes are stained with FITC Anti-Human CD3 Antibody and Biotin Anti-Human CD127/IL-7RA Antibody followed by Streptavidin-Elab Fluor® 647 (Left). Lymphocytes are stained with FITC Anti-Human CD3 Antibody and Biotin Mouse Rat IgG1, κ Isotype Control followed by with Streptavidin-Elab Fluor® 647 (Right).
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
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