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Biotin Anti-Mouse IL-17A Antibody[TC11-18H10.1]

Biotin Anti-Mouse IL-17A Antibody[TC11-18H10.1]
  • Biotin Anti-Mouse IL-17A Antibody[TC11-18H10.1]

Price: ¥1120.00 ¥400.00

Size:
100μg 25μg
  • 应用性: ICFCM
  • 亚型: Rat IgG1, κ
  • 宿主: Rat
Alternate Names
CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, Interleukin-17A
Cellular Localization
Secreted
Clone No
Isotype
Rat IgG1, κ
Leadtime
咨询
Background
IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
Abbre
IL-17A
Swissprot
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype Control
Applications
Form
Liquid
Concentration
0.5 mg/mL
Conjugation
Biotin
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Do not freeze.
Expiration Date
12个月
Shipping
冰袋
Gene ID
E-CK-A091 Cell Stimulation and Protein Transport Inhibitor Kit 500Assays , 200Assays , 100Assays , 50Assays
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
E-CK-A109 Intracellular Fixation/Permeabilization Buffer Kit 500Assays , 100Assays , 50Assays


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