Cell Ferrous Iron (Fe2+ ) Fluorometric Assay Kit

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中文名称：细胞亚铁离子（Fe2+ ）荧光法测试盒

货号：E-BC-F101
文献（102）
说明书

说明书

Cell Ferrous Iron (Fe2+ ) Fluorometric Assay Kit

Price: ¥1780.00

Size:

96 T

样本类型： 细胞
检测仪器及波长： 荧光酶标仪（Ex/Em=542 nm/575 nm）、流式细胞仪（Ex/Em=542 nm/575 nm）、荧光显微镜（Ex/Em=542 nm/570-620 nm）
研究领域： 无机盐离子;铁死亡

说明书或网站上未涉及的样本类型请先跟技术支持沟通，可进行售前验证

根据需测样本数，试剂盒测样本孔数和单个样本测量孔数来计算所需生化试剂盒数量，请点击按钮计算

检测原理	研究证实铁是生物体内量最多的过渡金属元素，其参与多种生理活动。近几年，细胞内的游离铁离子由于具有很高的反应性，和细胞损伤、死亡有一定的关联而得到了越来越多的关注。在细胞内游离铁离子以稳定的Fe²⁺和 Fe³⁺形式存在。从细胞内的还原环境、金属转运体及Fe²⁺的水溶性考虑，因此揭示细胞内Fe²⁺的行为比Fe³⁺更重要。本试剂盒提供一种荧光探针可以和Fe²⁺特异性结合，探针可以很好的进入到细胞内部，适用于活细胞内Fe²⁺的检测。当探针与Fe²⁺反应后，可以生成一种不可逆的橙色(红色)荧光产物(激发波长：542 nm，发射波长：575 nm)。
指标简称	Fe2+
检测时间	1 h 30 min
检测仪器及波长	荧光酶标仪（Ex/Em=542 nm/575 nm）、流式细胞仪（Ex/Em=542 nm/575 nm）、荧光显微镜（Ex/Em=542 nm/570-620 nm）
保存条件	该产品可在-20°C避光条件下保存6个月。
有效期	6个月

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IF: 14.300

Journal： Advanced Science (2025)

DOI：10.1002/advs.202411985

Reactivity：Mouse

Sample Type：hepatic tissue
Targeted inhibition of ferroptosis in bone marrow mesenchymal stem cells by engineered exosomes alleviates bone loss in smoking-related osteoporosis

IF: 8.700

Journal： Materials Today Bio (2025)

DOI：10.1016/j.mtbio.2025.101501

Reactivity：Mouse
MGST1 overexpression ameliorates mitochondrial dysfunction and ferroptosis during myocardial ischemia/reperfusion injury after heart transplantation

IF: 7.700

Journal： INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2025)

DOI：10.1016/j.ijbiomac.2025.140135

Reactivity：Mouse
TREM2 alleviates sepsis-induced acute lung injury by attenuating ferroptosis via the SHP1/STAT3 pathway

IF: 7.100

Journal： FREE RADICAL BIOLOGY AND MEDICINE (2025)

DOI：10.1016/j.freeradbiomed.2025.01.022

Reactivity：Mouse

Sample Type：lung tissue
Triptolide Alleviates Acute Lung Injury by Reducing Mitochondrial Dysfunction Mediated Ferroptosis Through the STAT3/p53 Pathway

IF: 7.100

Journal： FREE RADICAL BIOLOGY AND MEDICINE (2025)

DOI：10.1016/j.freeradbiomed.2025.02.001

Reactivity：Human,Mouse

Sample Type：lung tissue
Targeted temperature management alleviates post-resuscitation myocardial dysfunction by inhibiting ferroptosis

IF: 6.100

Journal： Cell Death Discovery (2025)

DOI：10.1038/s41420-025-02356-5

Reactivity：Rat
Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1

IF: 6.100

Journal： Journal of Translational Medicine (2025)

DOI：10.1186/s12967-025-06128-8

Reactivity：Human
Mechanistic study of METTL3 inducing ferroptosis to promote cervical cancer progression through mediating m6A modification of COTE-1

IF: 4.400

Journal： CELLULAR SIGNALLING (2025)

DOI：10.1016/j.cellsig.2025.111649

Reactivity：Human
Multimodal enhancement of ferroptosis for synergistic cascade colorectal cancer therapy

IF: 13.300

Journal： CHEMICAL ENGINEERING JOURNAL (2024)

DOI：10.1016/j.cej.2024.155048

Reactivity：Mouse
Liraglutide and GLP-1(9–37) alleviated hepatic ischemia-reperfusion injury by inhibiting ferroptosis via GSK3β/Nrf2 pathway and SMAD159/Hepcidin/FTH pathway

IF: 10.700

Journal： Redox Biology (2024)

DOI：10.1016/j.redox.2024.103468

Reactivity：Mouse,Human

Sample Type：liver tissue

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