Cell Ferrous Iron (Fe2+ ) Fluorometric Assay Kit

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中文名称：细胞亚铁离子（Fe2+ ）荧光法测试盒

货号：E-BC-F101
文献（102）
说明书

说明书

Cell Ferrous Iron (Fe2+ ) Fluorometric Assay Kit

Price: ¥1780.00

Size:

96 T

样本类型： 细胞
检测仪器及波长： 荧光酶标仪（Ex/Em=542 nm/575 nm）、流式细胞仪（Ex/Em=542 nm/575 nm）、荧光显微镜（Ex/Em=542 nm/570-620 nm）
研究领域： 无机盐离子;铁死亡

说明书或网站上未涉及的样本类型请先跟技术支持沟通，可进行售前验证

根据需测样本数，试剂盒测样本孔数和单个样本测量孔数来计算所需生化试剂盒数量，请点击按钮计算

检测原理	研究证实铁是生物体内量最多的过渡金属元素，其参与多种生理活动。近几年，细胞内的游离铁离子由于具有很高的反应性，和细胞损伤、死亡有一定的关联而得到了越来越多的关注。在细胞内游离铁离子以稳定的Fe²⁺和 Fe³⁺形式存在。从细胞内的还原环境、金属转运体及Fe²⁺的水溶性考虑，因此揭示细胞内Fe²⁺的行为比Fe³⁺更重要。本试剂盒提供一种荧光探针可以和Fe²⁺特异性结合，探针可以很好的进入到细胞内部，适用于活细胞内Fe²⁺的检测。当探针与Fe²⁺反应后，可以生成一种不可逆的橙色(红色)荧光产物(激发波长：542 nm，发射波长：575 nm)。
指标简称	Fe2+
检测时间	1 h 30 min
检测仪器及波长	荧光酶标仪（Ex/Em=542 nm/575 nm）、流式细胞仪（Ex/Em=542 nm/575 nm）、荧光显微镜（Ex/Em=542 nm/570-620 nm）
保存条件	该产品可在-20°C避光条件下保存6个月。
有效期	6个月

Natural flavonoids disrupt bacterial iron homeostasis to potentiate colistin efficacy

IF: 13.600

Journal： Science Advances (2023)

DOI：10.1126/sciadv.adg4205

PMID：37294761

Reactivity：Salmonella
Arbutin alleviates fatty liver by inhibiting ferroptosis via FTO/SLC7A11 pathway

IF: 11.400

Journal： Redox Biology (2023)

DOI：10.1016/j.redox.2023.102963

PMID：37984229

Reactivity：Mouse,Human

Sample Type：liver tissue
Identification of ZIP8-induced ferroptosis as a major type of cell death in monocytes under sepsis conditions

IF: 11.400

Journal： Redox Biology (2023)

DOI：10.1016/j.redox.2023.102985

PMID：38103342

Reactivity：Mouse
Polystyrene?nanoplastics lead to ferroptosis in the lungs

IF: 10.700

Journal： Journal of Advanced Research (2023)

DOI：10.1016/j.jare.2023.03.003

PMID：36933884

Reactivity：Human
Probiotics ameliorate benzene-induced systemic inflammation and hematopoietic toxicity by inhibiting Bacteroidaceae-mediated ferroptosis

IF: 9.800

Journal： SCIENCE OF THE TOTAL ENVIRONMENT (2023)

DOI：10.1016/j.scitotenv.2023.165678

PMID：37478946

Reactivity：Mouse

Sample Type：intestinal tissue
The iron matters: Aged microplastics disrupted the iron homeostasis in the liver organoids

IF: 9.800

Journal： SCIENCE OF THE TOTAL ENVIRONMENT (2023)

DOI：10.1016/j.scitotenv.2023.167529

PMID：37788777

Reactivity：Human

Sample Type：liver organoids (LOs)
PM2.5 exposure exacerbates seizure symptoms and cognitive dysfunction by disrupting iron metabolism and the Nrf2-mediated ferroptosis pathway

IF: 9.800

Journal： SCIENCE OF THE TOTAL ENVIRONMENT (2023)

DOI：10.1016/j.scitotenv.2023.168578

PMID：37981141

Reactivity：Mouse

Sample Type：hippocampus
VDAC2 malonylation participates in sepsis-induced myocardial dysfunction via mitochondrial-related ferroptosis

IF: 9.200

Journal： International Journal of Biological Sciences (2023)

DOI：10.7150/ijbs.84613

PMID：37416771

Reactivity：Rat

Sample Type：heart
Super-enhancer-driven MLX mediates redox balance maintenance via SLC7A11 in osteosarcoma

IF: 9.000

Journal： Cell Death & Disease (2023)

DOI：10.1038/s41419-023-05966-y

PMID：37460542

Reactivity：Human
Low-dose antimony exposure promotes prostate cancer proliferation by inhibiting ferroptosis via activation of the Nrf2-SLC7A11-GPX4 pathway

IF: 8.800

Journal： CHEMOSPHERE (2023)

DOI：10.1016/j.chemosphere.2023.139716

PMID：37562508

Reactivity：Mouse,Human

Sample Type：PC3 cell-Xenograft

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