Complement C3 Polyclonal Antibody(Capture/Detector)
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- 宿主： Rabbit
- 反应性： pig
- 应用性： ELISA Capture/Detector
| Verified Samples |
Verified Samples in ELISA: Recombinant Pig Complement C3 protein, Pig serum |
| Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Recombinant Pig Complement C3 protein expressed by E.coli |
| Abbre | Complement C3 |
| Synonyms | ASP, CPAMD1, AHUS5, ARMD9, C3a, C3b, |
| Swissprot | |
| Concentration | 1 mg/mL |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Immunology, Signal transduction |
| Conjugation | Unconjugated |
| Background | The complement system is an important effector which bridges the innate and adaptive immune systems . The third component of complement, C3, plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. Human C3, composed of α and β chains (115 and 75 kDa, respectively). Activation of C3 convertase cleaves the C3 α-subunit to generate C3a, which acts as an anaphylatoxin to mediate the local inflammatory response. C3b is further cleaved into iC3b, C3c, C3dg, and C3f. |
