Complement Factor H/CFH Polyclonal Antibody(Capture/Detector)
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- 宿主： Rabbit
- 反应性： Human
- 应用性： ELISA Capture/Detector
| Verified Samples |
Verified Samples in ELISA: Recombinant Human Complement Factor H/CFH protein, Human serum, Human plasma |
| Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Recombinant Human Complement Factor H/CFH protein expressed by Mammalian |
| Abbre | Complement Factor H/CFH |
| Synonyms | CF-H, AHUS1, AMBP1, FH, FHL1, ARMD4, ARMS1, CFHL3, HF, HF1, HF2, HUS, |
| Swissprot | |
| Concentration | 1 mg/mL |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Immunology |
| Conjugation | Unconjugated |
| Background | Complement factor H (CFH) is an abundant plasma glycoprotein that regulates the function of the alternative complement pathway in fluid phase and on cellular surfaces. Factor H binds to C3b,accelerates the decay of the alternative pathway C3-convertase (C3bBb) and acts as a cofactor for the factor I-mediated proteolytic inactivation of C3b. It plays a critical role in the homeostasis of the complement system in plasma and in the protection of bystander host cells and tissues from damage by complement activation. Abnormalities in factor H have been associated with renal disease. |
