Elab Fluor® 647 Anti-Mouse TNFα Antibody[XT3.11]
![Elab Fluor® 647 Anti-Mouse TNFα Antibody[XT3.11]](http://files.elabscience.cn/assets/images/loading.png)
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- 应用性: ICFCM
- 亚型: Rat IgG1, κ
- 宿主: Rat
Alternate Names | Tumor necrosis factor-α, Cachectin, Necrosin, Macrophage cytotoxic factor, Differentiation inducing factor, TNFSF-2, TNF-a, TNF-alpha |
Cellular Localization |
Secreted
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Clone No | |
Isotype | Rat IgG1, κ |
Leadtime |
咨询
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Background |
TNF-α is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells. Many transformed cell lines also secrete TNF-α. Monomeric mouse TNF-α is a 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD. TNF-α forms multimeric complexes; stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorrhagic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.
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Abbre | TNF-α |
Swissprot | |
Host | Rat |
Reactivity | Mouse |
Clonality | Monoclonal |
Isotype Control | |
Applications | |
Form | Liquid |
Concentration | 5 μL/Test |
Conjugation | Elab Fluor®647 |
Conjugation Information | Elab Fluor® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter). |
Spectrum | ![]() |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12个月 |
Shipping |
冰袋 |
Gene ID |
E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
E-CK-A109 | Intracellular Fixation/Permeabilization Buffer Kit | 500Assays , 100Assays , 50Assays |