Elab Fluor®700 Anti-Human CD196/CCR6 Antibody[G034E3]-Elabscience伊莱瑞特【官网】

Elab Fluor®700 Anti-Human CD196/CCR6 Antibody[G034E3]

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货号：E-AB-F1158M1
说明书

说明书

Elab Fluor®700 Anti-Human CD196/CCR6 Antibody[G034E3]

Price: ¥3420.00 ¥1440.00 ¥5100.00

Size:

100 Tests 20 Tests 100 Tests×2

应用性： FCM
亚型： Mouse IgG2b, κ
宿主： Mouse

Alternate Names	CMKBR6, GPR29, STRL22, CKRL3, GPRCY4, CCR6
Cellular Localization	Membrane
Clone No	G034E3
Isotype	Mouse IgG2b, κ
Leadtime	咨询
Background	CCR6, also known as CD196/CCR6, is a chemokine receptor that is expressed on immature dendritic cells, B lymphocytes, and memory T cells. CCR6 binds CCL20, although members of the β defensin family also bind CCR6 with a lower affinity. CCR6 positive cells, and its ligand CCL20, have been detected in numerous organs, especially the secondary lymphoid organ. CCL20 is selectively made by the follicle-associated epithelium (FAE) overlying Peyers Patches (PPs) and isolated lymphoid follicles (ILFs). CCL20 contributes to the recruitment of CCR6-expressing B cells to these structures. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells and is highly expressed on T cells resident in both normal and psoriatic skin. CCR6 and/or CCL20 have been implicated in the pathogenesis of rheumatoid arthritis and inflammatory bowel disease. Human T cells that are able to produce IL-17 express CCR6. It suggests that CCL20 and CCR6 have a role in inflammatory diseases by recruiting Th17 cells to target tissues.
Abbre	CD196
Swissprot	P51684
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	Elab Fluor®700 Mouse IgG2b, κ Isotype Control[MPC-11]
Applications	FCM
Form	Liquid
Conjugation	Elab Fluor®700
Conjugation Information	Elab Fluor^® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	1235

Staining of normal human peripheral blood cells with FITC Anti-Human CD19 Antibody[CB19] and Elab Fluor^®700 Anti-Human CD196/CCR6 Antibody[G034E3] (left) or Elab Fluor^®700 Mouse IgG2b, κ Isotype Control (right). Cells in the lymphocytes gate were used for analysis.