Elab Fluor®700 Anti-Human CD274/PD-L1 Antibody[29E.2A3]-Elabscience伊莱瑞特【官网】

Elab Fluor®700 Anti-Human CD274/PD-L1 Antibody[29E.2A3]

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货号：E-AB-F1133M1
说明书

说明书

Elab Fluor®700 Anti-Human CD274/PD-L1 Antibody[29E.2A3]

Price: ¥2640.00 ¥1080.00 ¥3960.00

Size:

100 Tests 20 Tests 100 Tests × 2

应用性： FCM
亚型： Mouse IgG2b, κ
宿主： Mouse

Alternate Names	B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, B7 homolog 1, B7-H, B7-H1, Programmed cell death ligand 1
Cellular Localization	Membrane
Clone No	29E.2A3
Isotype	Mouse IgG2b, κ
Leadtime	咨询
Background	CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
Abbre	PD-L1
Swissprot	Q9NZQ7
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	Elab Fluor®700 Mouse IgG2b, κ Isotype Control[MPC-11]
Applications	FCM
Form	Liquid
Conjugation	Elab Fluor®700
Conjugation Information	Elab Fluor^® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	29126

Staining of the U251 cells with Elab Fluor^®700 Anti-Human CD274/PD-L1 Antibody[29E.2A3](filled gray histogram) or Elab Fluor^®700 Mouse IgG2b, κ Isotype Control (empty black histogram). Total viable cells were used for analysis.