Elab Fluor®700 Anti-Human CD49d Antibody[HP1/2]-Elabscience伊莱瑞特【官网】

Elab Fluor®700 Anti-Human CD49d Antibody[HP1/2]

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货号：E-AB-F1359M1
说明书

说明书

Elab Fluor®700 Anti-Human CD49d Antibody[HP1/2]

Price: ¥3120.00 ¥1320.00 ¥4560.00

Size:

100 Tests 20 Tests 100 Tests × 2

应用性： FCM
亚型： Mouse IgG2a, κ
宿主： Mouse

Alternate Names	VLA-4 α chain, α4 integrin, Integrin α4 chain, ITGA4
Cellular Localization	Membrane
Clone No	HP1/2
Isotype	Mouse IgG2a, κ
Leadtime	咨询
Background	CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.
Abbre	CD49d
Swissprot	P13612
Host	Mouse
Reactivity	Human
Clonality	Recombinant
Isotype Control	Elab Fluor®700 Mouse IgG2a, κ Isotype Control[C1.18.4]
Applications	FCM
Form	Liquid
Conjugation	Elab Fluor®700
Conjugation Information	Elab Fluor^® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	3676

Staining of normal human peripheral blood cells with Elab Fluor^®700 Anti-Human CD49d Antibody[HP1/2](filled gray histogram) or Elab Fluor^®700 Mouse IgG2a, κ Isotype Control(empty black histogram). Cells in the lymphocytes gate were used for analysis.