Elab Fluor®700 Anti-Human IL-17A Antibody[BL168]-Elabscience伊莱瑞特【官网】

Elab Fluor®700 Anti-Human IL-17A Antibody[BL168]

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货号：E-AB-F1173M1
说明书

说明书

Elab Fluor®700 Anti-Human IL-17A Antibody[BL168]

Price: ¥3420.00 ¥1560.00 ¥5100.00

Size:

100 Tests 20 Tests 100 Tests × 2

应用性： FCM
亚型： Mouse IgG1, κ
宿主： Mouse

Alternate Names	IL17, CTLA-8, CTLA8, IL 17A
Cellular Localization	Secreted
Clone No	BL168
Isotype	Mouse IgG1, κ
Leadtime	咨询
Background	IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts; the enhancement of surface expression of ICAM-1 in fibroblasts; activation of NF-κB and costimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63%, 63%, and 72% amino acid sequence identity to rat IL-17A, mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS), respectively.
Abbre	IL-17A
Swissprot	Q16552
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	Elab Fluor®700 Mouse IgG1, κ Isotype Control[MOPC-21]
Applications	FCM
Form	Liquid
Conjugation	Elab Fluor®700
Conjugation Information	Elab Fluor^® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	3605

Intracellular staining of the 293T cells transfected with pcDNA3.1 plasmid encoding Human IL-17A gene with Elab Fluor^®700 Anti-Human IL-17A Antibody[BL168](filled gray histogram) or Elab Fluor^®700 Mouse IgG1, κ Isotype Control(empty black histogram). Total viable cells were used for analysis.

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