Elab Fluor®700 Anti-Mouse CD115/CSF-1R Antibody[AFS98]
![Elab Fluor®700 Anti-Mouse CD115/CSF-1R Antibody[AFS98]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： FCM
- 亚型： Rat IgG2a, κ
- 宿主： Rat
| Alternate Names | CD115, CSF-1 receptor (EC:2.7.10.1), CSF-1-R, CSF-1R, Csf1r, Csfmr, Fms, M-CSF-R, Macrophage colony-stimulating factor 1 receptor, Proto-oncogene c-Fms |
| Cellular Localization |
Membrane
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| Clone No | |
| Isotype | Rat IgG2a, κ |
| Leadtime |
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| Background |
CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.
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| Abbre | CD115 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype Control | |
| Applications | |
| Form | Liquid |
| Conjugation | Elab Fluor®700 |
| Conjugation Information | Elab Fluor® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter). |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
Staining of Balb/C murine abdominal macrophages with FITC Anti-Mouse/Human CD11b Antibody[M1/70] and Elab Fluor®700 Anti-Mouse CD115/CSF-1R Antibody[AFS98](left) or Elab Fluor®700 Rat IgG2a, κ Isotype Control(right).Total viable cells were used for analysis.
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
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