Elab Fluor® Red 780 Anti-Mouse CD8a Antibody[53-6.7] (无库存)
![Elab Fluor® Red 780 Anti-Mouse CD8a Antibody[53-6.7]](http://files.elabscience.cn/assets/images/loading.png)
Price:
- 应用性： FCM
- 亚型： Rat IgG2a, κ
- 宿主： Rat
| Alternate Names | CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2 |
| Cellular Localization |
Membrane
|
| Clone No | |
| Isotype | Rat IgG2a, κ |
| Leadtime |
咨询
|
| Background |
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
|
| Abbre | CD8a |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype Control | |
| Applications | |
| Form | Liquid |
| Concentration | 5 μL/Test |
| Conjugation | Elab Fluor®Red 780 |
| Conjugation Information | Elab Fluor® Red 780 is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 770 nm (e.g., a 780/60 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
-
Fusobacterium nucleatum-driven CX3CR1+ PD-L1+ phagocytes route to tumor tissues and reshape tumor microenvironment
IF: 12.200 -
Targeting oxidative phosphorylation to increase the efficacy of immune-combination therapy in renal cell carcinoma
IF: 10.300 -
Enhanced Cellular Immunity for Hepatitis B Virus Vaccine: A Novel Polyinosinic-Polycytidylic Acid-Incorporated Adjuvant Leveraging Cytoplasmic Retinoic Acid-Inducible Gene-Like Receptor Activation and Increased Antigen Uptake
IF: 8.100 -
Zingerone enhances the antitumor activity of attenuated Salmonella-mediated cancer immunotherapy by promoting tumor infiltration by host immune cells
IF: 3.800 -
Metformin enhances the anti-tumor effects mediated by attenuated Salmonella typhimurium
IF: 3.800Journal： Journal of Functional Foods (2024)Reactivity：MouseSample Type：CT26 cell-Xenograft -
Gut virome dysbiosis impairs antitumor immunity and reduces 5-fluorouracil treatment efficacy for colorectal cancer
IF: 3.500 -
Potentiating humoral and cellular immunity using a novel hybrid polymer-lipid nanoparticle adjuvant for HBsAg-VLP vaccine
IF: 10.200 -
Repurposing TAK875 as a novel STAT3 inhibitor for treating inflammatory bowel disease
IF: 5.800 -
IFN-γ enhances the antitumor activity of attenuated salmonella-mediated cancer immunotherapy by increasing M1 macrophage and CD4 and CD8 T cell counts and decreasing neutrophil counts
IF: 6.064Journal： Frontiers in Bioengineering and Biotechnology (2022)Reactivity：MouseSample Type：CT26 cell xenografts
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
