Fetuin B Polyclonal Antibody(Capture/Detector)

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- 宿主: Rabbit
- 反应性: Human
- 应用性: ELISA Capture/Detector;WB
Verified Samples |
Verified Samples in ELISA: Recombinant Human Fetuin B protein, Human serum, Human plasma Verified Samples in WB: Human plasma |
Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL, WB 1:500-1:1000 |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Immunogen | Recombinant Human Fetuin B Protein expressed by Mammalian |
Abbre | Fetuin B |
Synonyms | 16G, IRL, 16G2, 2310011O17Rik, AI255764, D17980, Fet, Fetuin beta, Fetuin-B, Fetuin-like protein, Fetuin-like protein IRL685, Gugu, IRL685, Pp63, FETUB |
Swissprot | |
Calculated MW | 42 kDa |
Observed MW | 45 kDa |
Concentration | 1 mg/mL |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Purification Method | Antigen Affinity Purification |
Research Areas | Cardiovascular, Neuroscience |
Conjugation | Unconjugated |
Background | Fetuins are members of the cystatin superfamily of cysteine protease inhibitors. Additional members of this superfamily are kininogen and histidine-rich glycoprotein. Fetuin A and B are two known members of the fetuin family. Hepatocytes are believed to be the principal cellular source, but other cell types also express it. Fetuin A, also known as alpha 2-Heremans-Schmid glycoprotein, is an inhibitor of basic calcium phosphate precipitation and a negative acute-phase protein. Normal circulating levels of Fetuin A in adults (300‑600 ug/mL) fall significantly (30‑50%) during injury and infection. Fetuin B is a newer member whose function is not fully characterized. Fetuin A and B display similarities and differences in their characteristics. Fetuin B exhibits reduction of calcification, while both mRNA levels were down‑regulated during the acute phase in inflammation-induced rats. However, they share only 20% amino acid sequence identity. The amounts of Fetuin B in human serum, unlike Fetuin A, vary with gender and are higher in females than in males. |
PDMH100300 | Recombinant Human Fetuin B Protein(Fc Tag) | 100 μg , 20 μg |