FITC Anti-Mouse CD172a/SIRPα Antibody[P84]
![FITC Anti-Mouse CD172a/SIRPα Antibody[P84]](http://files.elabscience.cn/assets/images/loading.png)
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- 应用性： FCM
- 亚型： Rat IgG1, κ
- 宿主： Rat
| Alternate Names | BIT, CD172 antigen-like family member A, P84, PTPNS1, SHPS-1, SIRPα |
| Cellular Localization |
Membrane
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| Clone No | |
| Isotype | Rat IgG1, κ |
| Leadtime |
咨询
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| Background |
CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.
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| Abbre | CD172a |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype Control | |
| Applications | |
| Form | Liquid |
| Conjugation | FITC |
| Conjugation Information | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
