FITC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]
![FITC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100μg
25μg
- 应用性: FCM
- 亚型: Rat IgG2a, κ
- 宿主: Rat
Alternate Names | TIMD3, HAVcr-2, TIM3, TIMD-3 |
Cellular Localization |
Membrane
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Clone No | |
Isotype | Rat IgG2a, κ |
Leadtime |
咨询
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Background |
CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
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Abbre | CD366 |
Swissprot | |
Host | Rat |
Reactivity | Mouse |
Clonality | Monoclonal |
Isotype Control | |
Applications | |
Form | Liquid |
Concentration | 0.5 mg/mL |
Conjugation | FITC |
Conjugation Information | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
Spectrum | ![]() |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12个月 |
Shipping |
冰袋 |
Gene ID |
C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Anti-Mouse CD366/Tim-3 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Rat IgG2a, κ Isotype Control (Right).
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Low-dose doxorubicin loaded extracellular vesicles combined Fas/FasL pathway-mediated chemo-sensitization and immunotherapy against tumor
IF: 5.300Journal: INTERNATIONAL JOURNAL OF PHARMACEUTICS (2024)Reactivity:MouseSample Type:3LL cell-Xenograft
E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |