FITC Anti-Mouse/Human CD11b Antibody[M1/70]
![FITC Anti-Mouse/Human CD11b Antibody[M1/70]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100μg
25μg
- 应用性: FCM
- 亚型: Rat IgG2b, κ
- 宿主: Rat
Alternate Names | CD11 antigen-like family member B, CD11b, CR-3 alpha chain, Integrin alpha-M, Itgam, Leukocyte adhesion receptor MO1 |
Cellular Localization |
Membrane
|
Clone No | |
Isotype | Rat IgG2b, κ |
Leadtime |
咨询
|
Background |
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
|
Abbre | CD11b |
Swissprot | |
Host | Rat |
Reactivity | Human;Mouse |
Clonality | Monoclonal |
Isotype Control | |
Applications | |
Form | Liquid |
Concentration | 0.5 mg/mL |
Conjugation | FITC |
Conjugation Information | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
Spectrum | ![]() |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12个月 |
Shipping |
冰袋 |
Gene ID |
C57BL/6 murine bone marrow cells are stained with FITC Anti-Mouse/Human CD11b Antibody (filled gray histogram). Unstained bone marrow cells (empty black histogram) are used as control.
-
Fusobacterium nucleatum-driven CX3CR1+ PD-L1+ phagocytes route to tumor tissues and reshape tumor microenvironment
IF: 12.200 -
SIRPB1 regulates inflammatory factor expression in the glioma microenvironment via SYK: functional and bioinformatics insights
IF: 6.100 -
Immunogenic Radiation Therapy for Enhanced Antitumor Immunity via a Core–Shell Nanosensitizer-Mediated Immunosuppressive Tumor Microenvironment Modulation
IF: 17.100Journal: ACS Nano (2023)PMID:37812400Reactivity:MouseSample Type:tumor-draining lymph nodes (TDLNs) -
Combination Therapy with Indigo and Indirubin for Ulcerative Colitis via Reinforcing Intestinal Barrier Function
IF: 7.310 -
Verbenalin alleviates acute lung injury induced by sepsis and IgG immune complex through GPR18 receptor
IF: 4.800 -
Antitumor effect of tubeimoside-I on murine colorectal cancers through PKM2-dependent pyroptosis and immunomodulation
IF: 3.600 -
Natural killer cells strengthen antitumor activity of cisplatin by immunomodulation and ameliorate cisplatin-induced side effects
IF: 2.000 -
Hepatocyte-Derived Prostaglandin E2-Modulated Macrophage M1-Type Polarization via mTOR-NPC1 Axis-Regulated Cholesterol Transport from Lysosomes to the Endoplasmic Reticulum in Hepatitis B Virus x Protein-Related Nonalcoholic Steatohepatitis
IF: 6.208 -
Geniposide inhibits SphK1 membrane targeting to restore macrophage polarization balance in collagen-induced arthritis mice
IF: 5.195 -
3,4-dihydroxyphenylethyl alcohol glycoside reduces acetaminophen-induced acute liver failure in mice by inhibiting hepatocyte ferroptosis and pyroptosis
IF: 2.984
E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |