FITC Anti-Mouse IL-17A Antibody[17F3]
![FITC Anti-Mouse IL-17A Antibody[17F3]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100μg
25μg
- 应用性： ICFCM
- 亚型： Mouse IgG1, κ
- 宿主： Mouse
| Alternate Names | Ctla8, Il17a, Interleukin-17A |
| Cellular Localization |
Secreted
|
| Clone No | |
| Isotype | Mouse IgG1, κ |
| Leadtime |
咨询
|
| Background |
The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-36A in vivo.
|
| Abbre | IL-17A |
| Swissprot | |
| Host | Mouse |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype Control | |
| Applications | |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Conjugation | FITC |
| Conjugation Information | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
HEK293T cells transiently transfected with pcDNA3.1 plasmid encoding Mouse IL-17A gene are stained with FITC Anti-Mouse IL-17A Antibody[17F3] (filled gray histogram) or FITC Mouse IgG1, κ Isotype Control (empty black histogram).
| E-CK-A091 | Cell Stimulation and Protein Transport Inhibitor Kit | 500Assays , 200Assays , 100Assays , 50Assays |
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
| E-CK-A109 | Intracellular Fixation/Permeabilization Buffer Kit | 500Assays , 100Assays , 50Assays |
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