Glutathione Peroxidase 1/GPX1 Polyclonal Antibody(Capture/Detector)
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- 宿主： Goat
- 反应性： Human
- 应用性： ELISA Capture/Detector
| Verified Samples |
Verified Samples in ELISA: Recombinant Human Glutathione Peroxidase 1/GPX1 protein, Human serum, Human plasma |
| Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
| Clonality | Polyclonal |
| Isotype | Goat IgG |
| Immunogen | Recombinant Human Glutathione Peroxidase 1/GPX1 protein expressed by E.coli |
| Abbre | Glutathione Peroxidase 1/GPX1 |
| Synonyms | GPX, Gpx-, Glutathione peroxidase, GPXD, GSHPX1, GPX1, GPx-1, GSHPx-1, Glutathione peroxidase 1, Cellular glutathione peroxidase |
| Swissprot | |
| Concentration | 1 mg/mL |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Background | This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
