ICAM-1/CD54 Monoclonal Antibody(Detector)
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- 宿主： Mouse
- 反应性： Rat
- 应用性： ELISA Detector
| Verified Samples |
Verified Samples in ELISA: Recombinant Rat ICAM-1/CD54 protein, Rat serum, Rat plasma |
| Dilution | ELISA Detector 0.1-0.4 μg/mL |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Immunogen | Recombinant Rat ICAM-1/CD54 Protein expressed by Mammalian |
| Abbre | ICAM-1/CD54 |
| Synonyms | InterceLLuLar adhesion moLecuLe 1, ICAM-1, CD54, Icam1, Icam-1 |
| Swissprot | |
| Concentration | 1 mg/mL |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Protein A/G Purification |
| Clone No. | 9E10 |
| Conjugation | Unconjugated |
| Background | ICAM-1 (intercellular adhesion molecule-1),also known as CD54,is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated lFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin,Fibrinogen,Hyaluronan,rhinoviruses,and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease,type 2 diabetes,organ transplant dysfunction,oxidant stress,increased abdominal fat mass,hypertension,liver disease,certain malignancies,and cerebral malaria. |
| AN001440P | ICAM-1/CD54 Monoclonal Antibody(Capture) | 100 μg , 25 μg , 1 mg |
