IL-29/IFN-λ1 Monoclonal Antibody(Capture/Detector)
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- 宿主： Mouse
- 反应性： Human
- 应用性： ELISA Capture/Detector
| Verified Samples |
Verified Samples in ELISA: Recombinant Human IL-29/IFN-λ1 protein, Human serum, Human plasma |
| Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Immunogen | Recombinant Human IL-29/IFN-λ1 protein expressed by Mammalian |
| Abbre | IL-29/IFN-λ1 |
| Synonyms | InterLeukin-29(IL-29), IFNL1, ZCYTO21, Interferon Lambda-1, IFN-Lambda-1, Cytokine Zcyto21, IL29 |
| Swissprot | |
| Concentration | 1 mg/mL |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Protein A/G Purification |
| Research Areas | Immunology, Microbiology |
| Clone No. | 1A6 |
| Conjugation | Unconjugated |
| Background | Cytokine with antiviral,antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense,predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of Il10RB and IFNlR1,and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG),which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNlR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression. |
