IL-8/CXCL8 Monoclonal Antibody(Detector)

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- 宿主: Rat
- 反应性: Human
- 应用性: ELISA Detector
Verified Samples |
Verified Samples in ELISA: Recombinant Human IL-8/CXCL8 protein, Human serum, Human plasma |
Dilution | ELISA Detector 0.1-0.4 μg/mL |
Clonality | Monoclonal |
Isotype | Rat IgG1 |
Immunogen | Recombinant Human IL-8/CXCL8 protein expressed by Mammalian |
Abbre | IL-8/CXCL8 |
Synonyms | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, 3-10C, AMCF-I, K60, |
Swissprot | |
Concentration | 1 mg/mL |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Purification Method | Protein A/G Purification |
Research Areas | Cancer, Cardiovascular, Immunology |
Clone No. | 3E8 |
Conjugation | Unconjugated |
Background | Interleukin 8 (IL-8),also known as CXCL8,which is a member of the CXC chemokine family. This chemokine is secreted by a variety of cell types including monocyte/macrophages,T cells,neutrophils,fibroblasts,endothelial cells,and various tumor cell lines in response to inflammatory stimuli. IL-8 has two primary functions. It induces chemotaxis in target cells,primarily neutrophils but also other granulocytes,causing them to migrate toward the site of infection. IL-8 also induces phagocytosis once they have arrived. This gene is believed to play a role in the pathogenesis of bronchiolitis,a common respiratory tract disease caused by viral infection. IL-8 is also known to be a potent promoter of angiogenesis. IL-8 has been associated with tumor angiogenesis,metastasis,and poor prognosis in breast cancer. IL-8 may present a novel therapeutic target for estrogen driven breast carcinogenesis and tumor progression. |
AN002140P | IL-8/CXCL8 Monoclonal Antibody(Capture) | 100 μg , 25 μg , 1 mg |