PE Anti-Human CD172a/b Antibody[SE5A5]-Elabscience伊莱瑞特【官网】

PE Anti-Human CD172a/b Antibody[SE5A5]

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货号：AN00317D
说明书

说明书

Price: ¥2364.00 ¥1164.00 ¥4248.00

Size:

100 Tests 20 Tests 100 Tests × 2

应用性： FCM
亚型： Mouse IgG1, κ
宿主： Mouse

Alternate Names	SIRPa, SIRPb, SIRPalpha/beta, BIT, SHPS1, MFR, P84, PTPNS1, CD172 antigen-like family member A, CD172 antigen-like family member B
Cellular Localization	Membrane
Clone No	SE5A5
Isotype	Mouse IgG1, κ
Leadtime	咨询
Background	CD172a, also known as signal-regulatory protein α (SIRPα), src homology 2 domain-containing phosphatase substrate-1 (SHPS1), PTPNS1, BIT, MFR, and P84, is a 75-110 kD transmembrane glycoprotein involved in receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily and is primarily expressed on monocytes/macrophages, granulocytes, dendritic cells, and neurons. CD172a serves as a substrate of activated receptor tyrosine kinases (RTKs). The interaction of CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion, and phagocytosis. CD47 (IAP) is the extracellular ligand for CD172a. SIRPα was recently demonstrated to be a specifc marker for cardiomyocytes derived from human pluripotent stem cells2.
Abbre	CD172a/b
Swissprot	O00241
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	PE Mouse IgG1, κ Isotype Control[MOPC-21]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PE
Conjugation Information	PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	140885

Staining of normal human peripheral blood cells with PE Anti-Human CD172a/b Antibody[SE5A5] (filled gray histogram) or PE Mouse IgG1, κ Isotype Control (empty black histogram). Cells in the granulocytes gate were used for analysis.