PE Anti-Human CD23 Antibody[EBVCS2]-Elabscience伊莱瑞特【官网】

PE Anti-Human CD23 Antibody[EBVCS2]

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货号：E-AB-F1382D
说明书

说明书

Price: ¥2160.00 ¥1020.00 ¥3720.00

Size:

100 Tests 20 Tests 100 Tests × 2

应用性： FCM
亚型： Mouse IgG1, κ
宿主： Mouse

Alternate Names	B6, BLAST-2, FcεRII, IgE Fc Receptor, Leu-20, Low affinity IgE receptor
Cellular Localization	Membrane
Clone No	EBVCS2
Isotype	Mouse IgG1, κ
Leadtime	咨询
Background	CD23 is a 45 kD protein, also known as Leu-20, FcεRII, IgE Fc receptor, BLAST-2, B6, and low affinity IgE receptor. It is a member of the Ig family, expressed on most mature B cells, B cells in follicular mantle (but not in proliferating germinal center cells, follicular dendritic cells, monocytes, eosinophils, Langerhans cells, and a subset of T cells (10-15% of tonsillar T cells). CD23 responds to high levels of IgE by downregulating IgE secretion. In human monocytes, CD23 triggering results in release of pro-inflammatory cytokines including TNF-α, IL-1, IL-6, and GM-CSF. CD23 can be proteolytically cleaved to generate soluble CD23 fragments of various molecular weights. In chronic lymphocytic leukemia, levels of soluble CD23 in the serum can be used as a prognostic marker to identify patients at high risk for disease progression. Alternate splicing of exon 2 can also generate two cell-surface isoforms of CD23 differing by 6 amino acids in their cytoplasmic region.
Abbre	CD23
Swissprot	P06734
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	PE Mouse IgG1, κ Isotype Control[MOPC-21]
Applications	FCM
Form	Liquid
Conjugation	PE
Conjugation Information	PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	2208

Staining of normal human peripheral blood cells with APC Anti-Human CD19 Antibody and PE Anti-Human CD23 Antibody[EBVCS2] (left) or PE Mouse IgG1, κ Isotype Control (right). Cells in the lymphocytes gate were used for analysis.