PE Anti-Human CD86 Antibody[BU63]
![PE Anti-Human CD86 Antibody[BU63]](http://files.elabscience.cn/assets/images/loading.png)
Price:
- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Alternate Names | Activation B7-2 antigen, Cd86, ETC-1, Early T-cell costimulatory molecule 1, T-lymphocyte activation antigen CD86 |
Cellular Localization |
Membrane
|
Clone No | |
Isotype | Mouse IgG1, κ |
Leadtime |
咨询
|
Background |
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
|
Abbre | CD86 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Isotype Control | |
Applications | |
Form | Liquid |
Concentration | 5 μL/Test |
Conjugation | PE |
Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
Spectrum | ![]() |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12个月 |
Shipping |
冰袋 |
Gene ID |
-
The Thyroid Hormone Analog GC-1 Mitigates Acute Lung Injury by Inhibiting M1 Macrophage Polarization
IF: 14.300 -
Overexpression of ornithine decarboxylase 1 mediates the immune-deserted microenvironment and poor prognosis in diffuse large B-cell lymphoma
IF: 7.600Journal: Journal of the National Cancer Center (2024)Reactivity:Human -
SIRPB1 regulates inflammatory factor expression in the glioma microenvironment via SYK: functional and bioinformatics insights
IF: 6.100 -
Cinobufagin modulates vasculogenic mimicry and tumor-associated macrophages to inhibit ovarian cancer progression
IF: 4.200 -
15-Deoxy-Δ-12,14-Prostaglandin J2 Represses Immune Escape of Lung Adenocarcinoma by Polarizing Macrophages Through Epidermal Growth Factor Receptor/Ras/Raf Pathway
IF: 3.200 -
SNHG12 in cancer-associated fibroblast-derived extracellular vesicle induces macrophage-myofibroblast transition
IF: 3.000 -
Electrical stimulation induces anti-tumor immunomodulation via a flexible microneedle-array-integrated interdigital electrode
IF: 18.900 -
Irreversible repolarization of tumour-associated macrophages by low-Pi stress inhibits the progression of hepatocellular carcinoma
IF: 5.300 -
CD96 Downregulation Promotes the Immune Response of CD4 T Cells and Associates with Ankylosing Spondylitis
IF: 3.411
E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |