PE Anti-Human HLA-DQ Antibody[1a3]-Elabscience伊莱瑞特【官网】

PE Anti-Human HLA-DQ Antibody[1a3]

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货号：AN00421D
说明书

说明书

Price: ¥2736.00 ¥792.00 ¥4104.00

Size:

100 Tests 20 Tests 100 Tests × 2

应用性： FCM
亚型： Mouse IgG2a, κ
宿主： Mouse

Alternate Names	MHC class II DQ monomorphic antigen, MHC II
Cellular Localization	Membrane
Clone No	1a3
Isotype	Mouse IgG2a, κ
Leadtime	咨询
Background	HLA-DQ is also known as MHC class II DQ monomorphic antigen. The major histocompatibility complex is composed of two heterodimeric glycoproteins (α and β chains) with apparent molecular weights of 27 and 32 kD. In contrast to other MHC class II molecules, both polypeptide chains of HLA-DQ are polymorphic, with the α chain showing an extremely high degree of polymorphism. HLA-DQ is expressed on B cells in the peripheral blood, and weakly expressed on activated T cells and some monocytes. HLA-DQ is absent on hematopoietic progenitors, resting T cells, erythrocytes, and platelets. HLA-DQ is expressed after HLA-DR and HLA-DP in hematopoietic development. HLA-DQ presents peptide fragments mainly from degraded intravesicular and extracellular proteins to CD4+ T lymphocytes. Specific alleles of HLA-DQ have been linked to the pathogenesis of several autoimmune diseases (including diabetes), both as a susceptibility and resistance factor depending on the particular polymorphism.
Abbre	HLA-DQ
Swissprot	P01906
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	PE Mouse IgG2a, κ Isotype Control[C1.18.4]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PE
Conjugation Information	PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	3117

Staining of normal human peripheral blood cells with PE Anti-Human HLA-DQ Antibody[1a3] (filled gray histogram) or PE Mouse IgG2a Isotype Control (empty black histogram). Cells in the lymphocytes gate were used for analysis.