PE Anti-Human IL-17A Antibody[BL168]
![PE Anti-Human IL-17A Antibody[BL168]](http://files.elabscience.cn/assets/images/loading.png)
Price:
- 应用性： ICFCM
- 亚型： Mouse IgG1, κ
- 宿主： Mouse
| Alternate Names | IL17, CTLA-8, CTLA8, IL 17A |
| Cellular Localization |
Secreted
|
| Clone No | |
| Isotype | Mouse IgG1, κ |
| Leadtime |
咨询
|
| Background |
IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts; the enhancement of surface expression of ICAM-1 in fibroblasts; activation of NF-κB and costimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63%, 63%, and 72% amino acid sequence identity to rat IL-17A, mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS), respectively.
|
| Abbre | IL-17A |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype Control | |
| Applications | |
| Form | Liquid |
| Concentration | 5 μL/Test |
| Conjugation | PE |
| Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
| E-CK-A091 | Cell Stimulation and Protein Transport Inhibitor Kit | 500Assays , 200Assays , 100Assays , 50Assays |
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
| E-CK-A109 | Intracellular Fixation/Permeabilization Buffer Kit | 500Assays , 100Assays , 50Assays |
