PE Anti-Mouse CD105 Antibody[MJ7/18]-Elabscience伊莱瑞特【官网】

PE Anti-Mouse CD105 Antibody[MJ7/18]

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货号：E-AB-F1233D
文献（3）
说明书

说明书

Price: ¥1740.00 ¥1020.00 ¥2640.00

Size:

100Tests 50Tests 100Tests×2

应用性： FCM
亚型： Rat IgG2a, κ
宿主： Rat

Alternate Names	END, Endoglin, Eng
Cellular Localization	Membrane
Clone No	MJ7/18
Isotype	Rat IgG2a, κ
Leadtime	咨询
Background	CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.
Abbre	CD105
Swissprot	Q63961
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype Control	PE Rat IgG2a, κ Isotype Control[2A3]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PE
Conjugation Information	PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	13805

Mouse endothelial cells (bEnd.3) are stained with PE Anti-Mouse CD105 Antibody (filled gray histogram). PE Mouse IgG2a, κ Isotype Control stained cells are used as control.