PE Anti-Mouse CD206/MMR Antibody[C068C2]（E-AB-F1135D）|-Elabscience伊莱瑞特【官网】

PE Anti-Mouse CD206/MMR Antibody[C068C2]

一键复制产品信息

货号：E-AB-F1135D
文献（57）
说明书

说明书

PE Anti-Mouse CD206/MMR Antibody[C068C2]

Price: ¥1440.00 ¥1080.00 ¥2280.00

Size:

100 Tests 50 Tests 100 Tests × 2

应用性： FCM;ICFCM
亚型： Rat IgG2a, κ
宿主： Rat

Alternate Names	MMR, MR, MRC1, macrophage mannose receptor, mannose receptor
Cellular Localization	Membrane;Endosome
Clone No	C068C2
Isotype	Rat IgG2a, κ
Leadtime	咨询
Background	CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.
Abbre	CD206
Swissprot	Q61830
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype Control	PE Rat IgG2a, κ Isotype Control[2A3]
Applications	FCM;ICFCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PE
Conjugation Information	PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	17533

C57BL/6 murine abdominal macrophages elicited by starch broth are stained with APC Anti-Mouse F4/80 Antibody and PE Anti-Mouse CD206 Antibody (Left). Abdominal macrophages are stained with APC Anti-Mouse F4/80 Antibody and PE Rat IgG2a, κ Isotype Control (Right).

Corilagin enhances wound healing by modulating the macrophage phenotype in diabetic mice

IF: 4.4

Journal： FASEB JOURNAL (2025)

DOI：10.1096/fj.202403085RR

Reactivity：Mouse
Diffuse large B-cell lymphoma cell-derived exosomal NSUN2 stabilizes PDL1 to promote tumor immune escape and M2 macrophage polarization in a YBX1-dependent manner

IF: 3.8

Journal： ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2025)

DOI：10.1016/j.abb.2025.110322

Reactivity：Human
Cationic liposomes encapsulating IL-2 selectively induce apoptosis and significantly reduce the secretion of cytokines on M1-murine polarized macrophages

IF: 3.7

Journal： CYTOKINE (2025)

DOI：10.1016/j.cyto.2025.156903

Reactivity：Mouse
Methotrexate loaded extracellular vesicles attenuate periodontitis by suppressing ACSL1 and promoting anti-inflammatory macrophage

IF: 3.2

Journal： MOLECULAR IMMUNOLOGY (2025)

DOI：10.1016/j.molimm.2025.04.005

Reactivity：Mouse
Nanomedicines Promote Cartilage Regeneration in Osteoarthritis by Synergistically Enhancing Chondrogenesis of Mesenchymal Stem Cells and Regulating Inflammatory Environment

IF: 15.8

Journal： ACS Nano (2024)

DOI：10.1021/acsnano.3c11848

Reactivity：Mouse
Carrier-Free Photodynamic Bioregulators Inhibiting Lactic Acid Efflux Combined with Immune Checkpoint Blockade for Triple-Negative Breast Cancer Immunotherapy

IF: 15.8

Journal： ACS Nano (2024)

DOI：10.1021/acsnano.4c07213

Reactivity：Mouse

Sample Type：4T1 cell-Xenograft,spleen tissue
Anti-pyroptosis biomimetic nanoplatform loading puerarin for myocardial infarction repair: From drug discovery to drug delivery

IF: 12.8

Journal： BIOMATERIALS (2024)

DOI：10.1016/j.biomaterials.2024.122890

Reactivity：Mouse
Arginine-assembly as NO nano-donor prevents the negative feedback of macrophage repolarization by mitochondrial dysfunction for cancer immunotherapy

IF: 12.8

Journal： BIOMATERIALS (2024)

DOI：10.1016/j.biomaterials.2024.122474

Reactivity：Mouse
MCT4-dependent lactate transport: a novel mechanism for cardiac energy metabolism injury and inflammation in type 2 diabetes mellitus

IF: 8.5

Journal： Cardiovascular Diabetology (2024)

DOI：10.1186/s12933-024-02178-2

Reactivity：Mouse
A self-gelling alginate/chitosan based powder containing bioactive nanoparticles for non-compressible bleeding control and promoting wound healing

IF: 7.7

Journal： INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2024)

DOI：10.1016/j.ijbiomac.2024.135722

Reactivity：Mouse

E-CK-A105	10×ACK Lysis Buffer	500 mL , 200 mL , 100 mL
E-CK-A107	Cell Staining Buffer	500 mL , 200 mL , 100 mL
E-CK-A109	Intracellular Fixation/Permeabilization Buffer Kit	500 Assays , 100 Assays , 50 Assays