PE Anti-Mouse CD86 Antibody[GL-1]
![PE Anti-Mouse CD86 Antibody[GL-1]](http://files.elabscience.cn/assets/images/loading.png)
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- 应用性： FCM
- 亚型： Rat IgG2a, κ
- 宿主： Rat
| Alternate Names | Activation B7-2 antigen, Cd86, ETC-1, Early T-cell costimulatory molecule 1, T-lymphocyte activation antigen CD86 |
| Cellular Localization |
Membrane
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| Clone No | |
| Isotype | Rat IgG2a, κ |
| Leadtime |
咨询
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| Background |
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
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| Abbre | CD86 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype Control | |
| Applications | |
| Form | Liquid |
| Concentration | 5 μL/Test |
| Conjugation | PE |
| Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
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IF: 5.600 -
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Cannabinoid receptor 2 alleviates sepsis-associated acute lung injury by modulating maturation of dendritic cells
IF: 5.600Journal： INTERNATIONAL IMMUNOPHARMACOLOGY (2023)PMID：37582314Reactivity：Mouse,HumanSample Type：Bronchoalveolar Lavage Fluid (BALF) -
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IFN-γ enhances the antitumor activity of attenuated salmonella-mediated cancer immunotherapy by increasing M1 macrophage and CD4 and CD8 T cell counts and decreasing neutrophil counts
IF: 6.064Journal： Frontiers in Bioengineering and Biotechnology (2022)Reactivity：MouseSample Type：CT26 cell xenografts -
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Development and validation of a microenvironment-related prognostic model for hepatocellular carcinoma patients based on histone deacetylase family
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κ/β-Carrageenan oligosaccharides promoting polarization of LPS-activated macrophage and their potential in diabetes wound healing
IF: 5.880Journal： Materials Science & Engineering C-Materials for Biological Applications (2020)PMID：33579508Reactivity：MouseSample Type：RAW264.7 cells
| E-CK-A105 | 10×ACK Lysis Buffer | 500 mL , 200 mL , 100 mL |
| E-CK-A107 | Cell Staining Buffer | 500 mL , 200 mL , 100 mL |
