PE Anti-Mouse CD8a Antibody[53-6.7]
![PE Anti-Mouse CD8a Antibody[53-6.7]](http://files.elabscience.cn/assets/images/loading.png)
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- 应用性： FCM
- 亚型： Rat IgG2a, κ
- 宿主： Rat
| Alternate Names | CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2 |
| Cellular Localization |
Membrane
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| Clone No | |
| Isotype | Rat IgG2a, κ |
| Leadtime |
咨询
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| Background |
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
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| Abbre | CD8a |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype Control | |
| Applications | |
| Form | Liquid |
| Concentration | 5 μL/Test |
| Conjugation | PE |
| Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
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Self-Activated Cascade Biocatalysis of Glucose Oxidase–Polycation–Iron Nanoconjugates Augments Cancer Immunotherapy
IF: 10.383 -
Comparative study of subcutaneous, intramuscular, and oral administration of bovine pathogenic Escherichia coli bacterial ghost vaccine in mice
IF: 8.786Journal： Frontiers in Immunology (2022)Reactivity：MouseSample Type：spleen tissue -
Na2S2O4@Co-metal organic framework (ZIF-67) @glucose oxidase for biofilm-infecting wound healing with immune activation
IF: 8.025Journal： INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)Reactivity：MouseSample Type：lymph nodes ,spleens -
Targeting Glutamine Metabolism Ameliorates Autoimmune Hepatitis via Inhibiting T Cell Activation and Differentiation.
IF: 7.561 -
IFN-γ enhances the antitumor activity of attenuated salmonella-mediated cancer immunotherapy by increasing M1 macrophage and CD4 and CD8 T cell counts and decreasing neutrophil counts
IF: 6.064Journal： Frontiers in Bioengineering and Biotechnology (2022)Reactivity：MouseSample Type：CT26 cell xenografts -
Epigallocatechin-3-gallate protects immunity and liver drug-metabolism function in mice loaded with restraint stress
IF: 6.530Journal： BIOMEDICINE & PHARMACOTHERAPY (2020)PMID：32570121Reactivity：MouseSample Type：Whole Blood -
Formaldehyde inhibits development of T lymphocytes in mice
IF: 1.050Journal： TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY (2020)Reactivity：MouseSample Type：Cell culture medium
| E-CK-A105 | 10×ACK Lysis Buffer | 500 mL , 200 mL , 100 mL |
| E-CK-A107 | Cell Staining Buffer | 500 mL , 200 mL , 100 mL |
