PE Anti-Mouse CD8a Antibody[53-6.7]
![PE Anti-Mouse CD8a Antibody[53-6.7]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100μg
25μg
- 应用性: FCM
- 亚型: Rat IgG2a, κ
- 宿主: Rat
Alternate Names | CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2 |
Cellular Localization |
Membrane
|
Clone No | |
Isotype | Rat IgG2a, κ |
Leadtime |
咨询
|
Background |
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
|
Abbre | CD8a |
Swissprot | |
Host | Rat |
Reactivity | Mouse |
Clonality | Monoclonal |
Isotype Control | |
Applications | |
Form | Liquid |
Concentration | 0.2 mg/mL |
Conjugation | PE |
Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
Spectrum | ![]() |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12个月 |
Shipping |
冰袋 |
Gene ID |
C57BL/6 murine splenocytes are stained with PE Anti-Mouse CD8a Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
-
Utilizing Engineered Bacteria as “Cell Factories” In Vivo for Intracellular RNA-Loaded Outer Membrane Vesicles’ Self-Assembly in Tumor Treatment
IF: 15.800 -
Biomimetic cascade-released hydrogel scaffolds from microfluidics for efficient T cell recruitment and expansion
IF: 13.300Journal: CHEMICAL ENGINEERING JOURNAL (2024)Reactivity:MouseSample Type:4T1 cell-Xenograft -
Spatially Confined Photoacoustic Effects of Responsive Nanoassembly Boosts Lysosomal Membrane Permeabilization and Immunotherapy of Triple-Negative Breast Cancer
IF: 9.400Journal: Acta Biomaterialia (2024)Reactivity:MouseSample Type:4T1 cell-Xenograft -
Osteosarcoma-targeting PtIV prodrug amphiphile for enhanced chemo-immunotherapy via Ca2+ trapping
IF: 9.400 -
Engineered Carrier-Free Nanosystem-Induced In Situ Therapeutic Vaccines for Potent Cancer Immunotherapy
IF: 8.300Journal: ACS Applied Materials & Interfaces (2024)Reactivity:MouseSample Type:4T1 cell-Xenograft -
Structural characterization and adjuvant activity of a water soluble polysaccharide from Poria cocos
IF: 7.700Journal: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2024)Reactivity:Mouse -
Chinese yam polysaccharide-loaded aluminium hydroxide nanoparticles used as vaccine adjuvant to induce potent humoral and cellular immune responses
IF: 7.700Journal: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2024)Reactivity:MouseSample Type:draining lymph node (dLNs) -
Discovery of Novel Isoquinoline Analogues as Dual Tubulin Polymerization/V-ATPase Inhibitors with Immunogenic Cell Death Induction
IF: 6.800 -
Discovery of the First-in-Class Dual-Target ROCK/HDAC Inhibitor with Potent Antitumor Efficacy in Vivo That Trigger Antitumor Immunity
IF: 6.800 -
Enhancing Tumor-Specific immunity with SLdacA: A attenuated Salmonella-mediated c-di-AMP delivery system targeting the STING pathway
IF: 5.300Journal: INTERNATIONAL JOURNAL OF PHARMACEUTICS (2024)Reactivity:Mouse
E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |