PE/Cyanine5 Anti-Mouse CD122/IL-2RB Antibody[5H4]
![PE/Cyanine5 Anti-Mouse CD122/IL-2RB Antibody[5H4]](http://files.elabscience.cn/assets/images/loading.png)
Price:
- 应用性: FCM
- 亚型: Rat IgG2a, κ
- 宿主: Rat
Alternate Names | IL-2R subunit beta, CD122, High affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2RB, Il2rb, Interleukin-2 receptor subunit beta, p70-75 |
Cellular Localization |
Membrane
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Clone No | |
Isotype | Rat IgG2a, κ |
Leadtime |
咨询
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Background |
CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
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Abbre | CD122 |
Swissprot | |
Host | Rat |
Reactivity | Mouse |
Clonality | Monoclonal |
Isotype Control | |
Applications | |
Form | Liquid |
Concentration | 5 μL/Test |
Conjugation | PE/Cyanine 5 |
Conjugation Information | PE/Cyanine5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter). |
Spectrum | ![]() |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12个月 |
Shipping |
冰袋 |
Gene ID |
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Multifunctional nanoadjuvant-driven microenvironment modulation for enhanced photothermal immunotherapy in breast cancer
IF: 10.800Journal: JOURNAL OF CONTROLLED RELEASE (2023)PMID:37634552Reactivity:MouseSample Type:4T1 cell-xenograft
E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |