PerCP Anti-Human CD8a Antibody[OKT-8]
![PerCP Anti-Human CD8a Antibody[OKT-8]](http://files.elabscience.cn/assets/images/loading.png)
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- 应用性: FCM
- 亚型: Mouse IgG2a, κ
- 宿主: Mouse
Alternate Names | CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2 |
Cellular Localization |
Membrane
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Clone No | |
Isotype | Mouse IgG2a, κ |
Leadtime |
咨询
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Background |
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
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Abbre | CD8 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Applications | |
Form | Liquid |
Concentration | 5 μL/Test |
Conjugation | PerCP |
Conjugation Information | PerCP is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter). |
Spectrum | ![]() |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12个月 |
Shipping |
冰袋 |
Gene ID |
-
Hypoxia-induced autophagy in pancreatic cancer counteracts the cytotoxicity of CD8+ T cells by inhibiting the expression of MHC-I
IF: 5.000 -
APLNR inhibited nasopharyngeal carcinoma growth and immune escape by downregulating PD-L1
IF: 4.800
E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |