PerCP/Cyanine5.5 Anti-Mouse CD45 Antibody[30-F11]
![PerCP/Cyanine5.5 Anti-Mouse CD45 Antibody[30-F11]](http://files.elabscience.cn/assets/images/loading.png)
Price:
- 应用性： FCM
- 亚型： Rat IgG2b, κ
- 宿主： Rat
| Alternate Names | CD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200 |
| Cellular Localization |
Membrane
|
| Clone No | |
| Isotype | Rat IgG2b, κ |
| Leadtime |
咨询
|
| Background |
CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
|
| Abbre | CD45 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype Control | |
| Applications | |
| Form | Liquid |
| Concentration | 5 μL/Test |
| Conjugation | PerCP/Cyanine 5.5 |
| Conjugation Information | PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
-
An in-situ peptide-antibody self-assembly to block CD47 and CD24 signaling enhances macrophage-mediated phagocytosis and anti-tumor immune responses
IF: 14.700Journal： Nature Communications (2024)Reactivity：MouseSample Type：4T1 cell-Xenograft -
Macrophage membrane-reversibly camouflaged nanotherapeutics accelerate fracture healing by fostering MSCs recruitment and osteogenic differentiation
IF: 10.600Journal： JOURNAL OF NANOBIOTECHNOLOGY (2024)Reactivity：MouseSample Type：bone tissue -
Discovery of the First-in-Class Dual-Target ROCK/HDAC Inhibitor with Potent Antitumor Efficacy in Vivo That Trigger Antitumor Immunity
IF: 6.800 -
Spinal HMGB1 participates in the early stages of paclitaxel-induced neuropathic pain via microglial TLR4 and RAGE activation
IF: 5.700 -
Cannabidiol alleviates suture-induced corneal pathological angiogenesis and inflammation by inducing myeloid-derived suppressor cells
IF: 4.800Journal： INTERNATIONAL IMMUNOPHARMACOLOGY (2024)Reactivity：MouseSample Type：spleen tissue -
Hepatocyte growth factor is protective in early stage but bone-destructive in late stage of experimental periodontitis
IF: 3.400Journal： JOURNAL OF PERIODONTAL RESEARCH (2024)Reactivity：MouseSample Type：periodontal tissue -
Rod-Shaped Polymeric Nanoparticles Intervene Neutrophils for Efficient Ischemic Stroke Therapy
IF: 19.000Journal： ADVANCED FUNCTIONAL MATERIALS (2023)Reactivity：MouseSample Type：brain -
Promising alternatives of CD47 monoclonal antibody: an injectable degradable hydrogel loaded with PQ912 for postoperative immunotherapy effectively blocks CD47-SIRPα signal
IF: 11.600 -
An injectable superior depot of Telratolimod inhibits post-surgical tumor recurrence and distant metastases
IF: 8.947 -
Dendrobium fimbriatum Hook polysaccharide ameliorates dextran-sodium-sulfate-induced colitis in mice via improving intestinal barrier function, modulating intestinal microbiota, reducing oxidative stress and inflammatory responses
IF: 5.396
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
