Purified Anti-Human CD45 Antibody[HI30]
![Purified Anti-Human CD45 Antibody[HI30]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： FCM;IHC
- 亚型： Mouse IgG1, κ
- 宿主： Mouse
| Alternate Names | CD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200 |
| Clone No | |
| Isotype | Mouse IgG1, κ |
| Leadtime |
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| Verified Samples | Verified Samples in FCM: Human peripheral blood;Verified Samples in IHC: Human tonsil |
| Dilution |
FCM 2 μg/mL(1×105-5×105 cells);IHC 1:50-1:100
|
| Background |
CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
|
| Immunogen | Recombinant Human CD45 protein |
| Abbre | CD45 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Applications | |
| Research Areas | Cell Biology;Immunology;Inhibitory Molecules;Innate Immunity;Neuroscience;Neuroscience Cell Markers;Stem Cells |
| Concentration | ≥ 1 mg/mL |
| Conjugation | Unconjugated |
| Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12个月 |
| Shipping |
Ice bag |
Human peripheral blood were stained with 0.2 μg Purified Anti-Human CD45 Antibody[HI30] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Immunohistochemistry of paraffin-embedded Human tonsil using CD45 Monoclonal Antibody at dilution of 1:100.
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PITPNC1 Suppress CD8+ T cell immune function and promote radioresistance in rectal cancer by modulating FASN/CD155
IF: 6.100Journal： Journal of Translational Medicine (2024)Reactivity：Mouse,Human -
Catalpol Enhances Osteogenic Differentiation of Human Periodontal Stem Cells and Modulates Periodontal Tissue Remodeling in an Orthodontic Tooth Movement Rat Model
IF: 4.700 -
Exosome from hypoxia-conditioned apical papilla stem cells delivers JAG1 to accelerate angiogenesis in vitro through Notch signal
IF: 2.600
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
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